Proceedings

Bovine tuberculosis at the human-livestock-wildlife interface: Is it a public health problem in Tanzania? A review

Bugwesa Z. Katale, Erasto V. Mbugi, Sharon Kendal, Robert D. Fyumagwa, Gibson S. Kibiki, Peter Godfrey-Faussett, Julius D. Keyyu, Paul van Helden, Mecky I. Matee
Onderstepoort Journal of Veterinary Research | Vol 79, No 2 | a463 | DOI: https://doi.org/10.4102/ojvr.v79i2.463 | © 2012 Bugwesa Z. Katale, Erasto V. Mbugi, Sharon Kendal, Robert D. Fyumagwa, Gibson S. Kibiki, Peter Godfrey-Faussett, Julius D. Keyyu, Paul van Helden, Mecky I. Matee | This work is licensed under CC Attribution 4.0
Submitted: 12 June 2012 | Published: 20 June 2012

About the author(s)

Bugwesa Z. Katale, Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Tanzania, United Republic of
Erasto V. Mbugi, Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Tanzania, United Republic of
Sharon Kendal, Centre for Emerging, Endemic and Exotic disease, Royal Veterinary College, United Kingdom
Robert D. Fyumagwa, Tanzania Wildlife Research Institute, Njiro, Arusha, Tanzania, United Republic of
Gibson S. Kibiki, Kilimanjaro Christian Medical College, Kilimanjaro Clinical Research Institute, Tumaini University, Moshi, Tanzania, United Republic of
Peter Godfrey-Faussett, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
Julius D. Keyyu, Tanzania Wildlife Research Institute, Njiro, Arusha, Tanzania, United Republic of
Paul van Helden, DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/MRC Centre of Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, South Africa
Mecky I. Matee, Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Tanzania, United Republic of

Abstract

Despite the apparent public health concern about Bovine tuberculosis (BTB) in Tanzania, little has been done regarding the zoonotic importance of the disease and raising awareness of the community to prevent the disease. Bovine tuberculosis is a potential zoonotic disease that can infect a variety of hosts, including humans. The presence of multiple hosts including wild animals, inefficient diagnostic techniques, absence of defined national controls and eradication programs could impede the control of bovine TB. In Tanzania, the diagnosis of Mycobacterium bovis in animals is mostly carried out by tuberculin skin testing, meat inspection in abattoirs and only rarely using bacteriological techniques. The estimated prevalence of BTB in animals in Tanzania varies and ranges across regions from 0.2% to 13.3%, which is likely to be an underestimate if not confirmed by bacteriology or molecular techniques. Mycobacterium bovis has been detected and isolated from different animal species and has been recovered in 10% of apparently healthy wildebeest that did not show lesions at post-mortem. The transmission of the disease from animals to humans can occur directly through the aerosol route and indirectly by consumption of raw milk. This poses an emerging disease threat in the current era of HIV confection in Tanzania and elsewhere. Mycobacterium bovis is one of the causative agents of human extra pulmonary tuberculosis. In Tanzania there was a significant increase (116.6%) of extrapulmonary cases reported between 1995 and 2009, suggesting the possibility of widespread M. bovis and Mycobacterium tuberculosis infection due to general rise of Human Immunodeficiency virus (HIV). This paper aims to review the potential health and economic impact of bovine tuberculosis and challenges to its control in order to safeguard human and animal population in Tanzania.

Keywords

M. bovis; human-livestock-wildlife-interface; public health problem; Tanzania

Metrics

Total abstract views: 10267
Total article views: 20192

 

Crossref Citations

1. Evaluation and application of a milk antibody ELISA for assessing the prevalence and incidence of bovine tuberculosis in dairy herds in Hubei Province, China
Yingyu Chen, Shuang Cheng, Yu Wang, Guiqiang Wang, Xijuan Wu, Ian D. Robertson, Aizhen Guo
Animal Diseases  vol: 3  issue: 1  year: 2023  
doi: 10.1186/s44149-023-00069-9

2. Evidence, Challenges, and Knowledge Gaps Regarding Latent Tuberculosis in Animals
Pamela Ncube, Bahareh Bagheri, Wynand Johan Goosen, Michele Ann Miller, Samantha Leigh Sampson
Microorganisms  vol: 10  issue: 9  first page: 1845  year: 2022  
doi: 10.3390/microorganisms10091845

3. Bayesian Assessment of the Accuracy of a PCR-Based Rapid Diagnostic Test for Bovine Tuberculosis in Swine
Soledad Barandiaran, María Sol Pérez Aguirreburualde, María Jimena Marfil, Marcela Martínez Vivot, Natalia Aznar, Martín Zumárraga, Andrés M. Perez
Frontiers in Veterinary Science  vol: 6  year: 2019  
doi: 10.3389/fvets.2019.00204

4. Molecular characterization and antimicrobial resistance profiles of Mycobacterium tuberculosis complex in environmental substrates from three dairy farms in Eastern Cape, South Africa
Athini Ntloko, Martins Ajibade Adefisoye, Ezekiel Green
International Journal of Environmental Health Research  vol: 31  issue: 2  first page: 215  year: 2021  
doi: 10.1080/09603123.2019.1642458

5. Community Knowledge, Attitude and Practices towards Tuberculosis among Household Heads in Mogadishu, Somalia
Mohamed Yusuf - Isleged
Integrated Journal for Research in Arts and Humanities  vol: 2  issue: 5  first page: 74  year: 2022  
doi: 10.55544/ijrah.2.5.13

6. A continuous time Markov chain model for the dynamics of bovine tuberculosis in humans and cattle
Mussa A. Stephano, Jacob I. Irunde, Joshua A. Mwasunda, Chacha S. Chacha
Ricerche di Matematica  vol: 73  issue: 4  first page: 1815  year: 2024  
doi: 10.1007/s11587-022-00696-3

7. Comparison of bovine tuberculosis recurrence in Irish herds between 1998 and 2008
M.J. Gallagher, I.M. Higgins, T.A. Clegg, D.H. Williams, S.J. More
Preventive Veterinary Medicine  vol: 111  issue: 3-4  first page: 237  year: 2013  
doi: 10.1016/j.prevetmed.2013.05.004

8. Bovine tuberculosis in Central Ethiopian slaughterhouses and the identification of causative mycobacteria by multiplex real-time PCR
Abebe Fromsa, Andrew J.K. Conlan, Sreenidhi Srinivasan, Miserach Zeleke, Dawit Worku, Matios Lakew, Musse Girma Abdela, Getahun Bahiru, James L.N. Wood, Douwe Bakker, Balako Gumi, Gobena Ameni, Vivek Kapur
BMC Microbiology  vol: 24  issue: 1  year: 2024  
doi: 10.1186/s12866-024-03543-7

9. Isolation and Potential for Transmission ofMycobacterium bovisat Human-livestock-wildlife Interface of the Serengeti Ecosystem, Northern Tanzania
B. Z. Katale, E. V. Mbugi, K. K. Siame, J. D. Keyyu, S. Kendall, R. R. Kazwala, H. M. Dockrell, R. D. Fyumagwa, A. L. Michel, M. Rweyemamu, E. M. Streicher, R. M. Warren, P. van Helden, M. I. Matee
Transboundary and Emerging Diseases  vol: 64  issue: 3  first page: 815  year: 2017  
doi: 10.1111/tbed.12445

10. Cattle‐associated risk factors for human tuberculosis in rural livestock‐keeping communities, Uganda
Julianne Meisner, Kellie Curtis, Thomas W. Graham, Michael B. Apamaku, Lisa E. Manhart, Peter M. Rabinowitz
Zoonoses and Public Health  vol: 66  issue: 1  first page: 73  year: 2019  
doi: 10.1111/zph.12530

11. Cystic echinococcosis dynamics in dogs, humans and cattle: Deterministic and stochastic modeling
Chacha S. Chacha, Mussa A. Stephano, Jacob I. Irunde, Joshua A. Mwasunda
Results in Physics  vol: 51  first page: 106697  year: 2023  
doi: 10.1016/j.rinp.2023.106697

12. Prevalence and Demographic Risk Factors of Mycobacterium tuberculosis Infections in Captive Asian Elephants (Elephas maximus) Based on Serological Assays
Taweepoke Angkwanish, Hans J. C. M. Vernooij, Anucha Sirimalaisuwan, Pattara Charernpan, Mirjam Nielen, Victor P. M. G. Rutten
Frontiers in Veterinary Science  vol: 8  year: 2021  
doi: 10.3389/fvets.2021.713663

13. Conventional knowledge, general attitudes and risk perceptions towards zoonotic diseases among Maasai in northern Tanzania
E.R. Kriegel, D.J.R. Cherney, C. Kiffner
Heliyon  vol: 7  issue: 5  first page: e07041  year: 2021  
doi: 10.1016/j.heliyon.2021.e07041

14. Risk factors associated with Mycobacterium bovis skin positivity in cattle and buffalo in Peshawar, Pakistan
Irfan Khattak, Muhammad Hassan Mushtaq, Mansur ud Din Ahmad, Muhammad Sarwar Khan, Mamoona chaudhry, Umer Sadique
Tropical Animal Health and Production  vol: 48  issue: 3  first page: 479  year: 2016  
doi: 10.1007/s11250-015-0976-3

15. Tuberculin screening of some selected Fulani lactating cows in North-Central Nigeria
Aishatu Abubakar, Lushaikyaa Allam, Solomon O. Okaiyeto, Ayuba Caleb Kudi, Shehu U. Abdullahi, Peter H. Brooks, Madhu Goyal
Tropical Animal Health and Production  vol: 45  issue: 7  first page: 1505  year: 2013  
doi: 10.1007/s11250-013-0389-0

16. Molecular characterization of Mycobacterium bovis isolates from pastoral livestock at Mikumi-Selous ecosystem in the eastern Tanzania
Richard S. Mwakapuja, Zachariah E. Makondo, Joseph Malakalinga, Irmgard Moser, Rudovick R. Kazwala, Manfred Tanner
Tuberculosis  vol: 93  issue: 6  first page: 668  year: 2013  
doi: 10.1016/j.tube.2013.08.002

17. Survey of the knowledge, attitude and perceptions on bovine tuberculosis in Mnisi community, Mpumalanga, South Africa
Rudo Marange, Darshana Morar-Leather, Folorunso O. Fasina
Onderstepoort Journal of Veterinary Research  vol: 87  issue: 1  year: 2020  
doi: 10.4102/ojvr.v87i1.1808

18. Screening putative antigens as stimulators in the Mycobacterium bovis interferon-gamma release assay for cattle
Chuang Meng, Ting Wan, Zhengzhong Xu, Yan Liu, Fa Shan, Lin Sun, Yuelan Yin, Xiang Chen, Xinan Jiao
Veterinary Immunology and Immunopathology  vol: 168  issue: 1-2  first page: 111  year: 2015  
doi: 10.1016/j.vetimm.2015.09.001

19. Prevalence and significant geospatial clusters of bovine tuberculosis infection at livestock–wildlife interface ecosystem in Eastern Tanzania
Richard Simon Mwakapuja, Zachariah Ephraim Makondo, Joseph Malakalinga, Ward Bryssinckx, Robinson Hammerthon Mdegela, Irmgard Moser, Rudovick Reuben Kazwala, Manfred Tanner
Tropical Animal Health and Production  vol: 45  issue: 5  first page: 1223  year: 2013  
doi: 10.1007/s11250-013-0350-2

20. Mycobacteria and Disease in Southern Africa
L. Botha, N. C. Gey van Pittius, P. D. van Helden
Transboundary and Emerging Diseases  vol: 60  first page: 147  year: 2013  
doi: 10.1111/tbed.12159

21. Prevalence of tuberculosis, brucellosis and trypanosomiasis in cattle in Tanzania: a systematic review and meta-analysis
Silvia Alonso, Ian Dohoo, Johanna Lindahl, Cristobal Verdugo, Isaiah Akuku, Delia Grace
Animal Health Research Reviews  vol: 17  issue: 1  first page: 16  year: 2016  
doi: 10.1017/S146625231600013X

22. Prevalence of bovine tuberculosis in slaughtered cattle identified by nested-PCR in abattoirs from two dairy areas of Ecuador
Gustavo Echeverría, Lenin Ron, Ana María León, Wilson Espinosa, Washington Benítez-Ortiz, Freddy Proaño-Pérez
Tropical Animal Health and Production  vol: 46  issue: 6  first page: 1015  year: 2014  
doi: 10.1007/s11250-014-0610-9

23. SCREENING FOR BOVINE TUBERCULOSIS IN AFRICAN BUFFALO (SYNCERUS CAFFER) IN NGORONGORO CONSERVATION AREA, NORTHERN TANZANIA: IMPLICATIONS FOR PUBLIC HEALTH
Bugwesa Z. Katale, Robert D. Fyumagwa, Eblate E. Mjingo, Kuya Sayalel, Emmanuel K. Batamuzi, Mecky I. Matee, Julius D. Keyyu, Justice Muumba, Maulid Mdaki, Erasto V. Mbugi, Mark M. Rweyemamu, Donald G. Mpanduji
Journal of Wildlife Diseases  vol: 53  issue: 4  first page: 711  year: 2017  
doi: 10.7589/2016-10-223

24. Wild Animal Tuberculosis: Stakeholder Value Systems and Management of Disease
Eamonn Gormley, Leigh A. L. Corner
Frontiers in Veterinary Science  vol: 5  year: 2018  
doi: 10.3389/fvets.2018.00327

25. Bovine tuberculosis at the human–livestock–wildlife interface and its control through one health approach in the Ethiopian Somali Pastoralists: A review
Abdifetah Mohamed
One Health  vol: 9  first page: 100113  year: 2020  
doi: 10.1016/j.onehlt.2019.100113

26. Risk Factors for Zoonotic Tuberculosis at the Wildlife–Livestock–Human Interface in South Africa
Petronillah R. Sichewo, Anita L. Michel, Jolly Musoke, Eric M.C. Etter
Pathogens  vol: 8  issue: 3  first page: 101  year: 2019  
doi: 10.3390/pathogens8030101