Original Research

Experimental infections of baboons (Papio spp.) and vervet monkeys (Cercopithecus aethiops) with Trichinella zimbabwensis and successful treatment with ivermectin

S. Mukaratirwa, B. M. Dzoma, E. Matenga, S. D. Ruziwa, L. Sacchi, E. Pozio
Onderstepoort Journal of Veterinary Research | Vol 75, No 2 | a16 | DOI: https://doi.org/10.4102/ojvr.v75i2.16 | © 2008 S. Mukaratirwa, B. M. Dzoma, E. Matenga, S. D. Ruziwa, L. Sacchi, E. Pozio | This work is licensed under CC Attribution-NoDerivatives 4.0
Submitted: 31 August 2008 | Published: 31 August 2008

About the author(s)

S. Mukaratirwa, Department of Paraclinical Veterinary Studies, Faculty of Veterinary Science, University of Zimbabwe, P.O. Box MP 167 Mount Pleasant Harare, Zimbabwe, Zimbabwe
B. M. Dzoma, Department of Paraclinical Veterinary Studies, Faculty of Veterinary Science, University of Zimbabwe, P.O. Box MP 167 Mount Pleasant Harare, Zimbabwe
E. Matenga, Department of Paraclinical Veterinary Studies, Faculty of Veterinary Science, University of Zimbabwe, P.O. Box MP 167 Mount Pleasant Harare, Zimbabwe
S. D. Ruziwa, Department of Paraclinical Veterinary Studies, Faculty of Veterinary Science, University of Zimbabwe, P.O. Box MP 167 Mount Pleasant Harare, Zimbabwe
L. Sacchi, Department of Animal Biology, University of Pavia, Piazza Botta 9, 27100 Pavia, ltaly
E. Pozio, Department of Infectious, Parasitic and lmmunomediated Diseases, Rome, ltaly

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Abstract

Experimental Trichinella zimbabwensis infections were established in three baboons (Papios p.)and four vervet monkeys (Cercopithecuase thiops) and the clinical-pathological manifestations assessed. The infected animals showed clinical signs ranging from fever, diarrhoea, periorbitaol edema and muscular pain in varying degrees. One baboon became blind due to the infection. Levels of creatinine phosphokinase and lactated ehydrogenase increased to reach a peak on Day 42 post-infection(pi)for both baboons and monkeys. Blood parameters such as packed cell volume, levels of red blood cells and white blood cells did not change significantly from the normal ranges except for the levels of eosinophils which peaked above the normal ranges at Day 28 and 56 pi in baboons and at Day 56 pi in monkeys.

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Crossref Citations

1. Trichinella zimbabwensis in a naturally infected mammal
L.J. La Grange, G. Marucci, E. Pozio
Journal of Helminthology  vol: 84  issue: 01  first page: 35  year: 2010  
doi: 10.1017/S0022149X09990241