Original Research

Determination of the optimal time of vaccination against infectious bursal disease virus (Gumboro) in Algeria

Omar Besseboua, Abdelhanine Ayad, Hama Benbarek
Onderstepoort Journal of Veterinary Research | Vol 82, No 1 | a887 | DOI: https://doi.org/10.4102/ojvr.v82i1.887 | © 2015 Omar Besseboua, Abdelhanine Ayad, Hama Benbarek | This work is licensed under CC Attribution-NoDerivatives 4.0
Submitted: 20 September 2014 | Published: 30 April 2015

About the author(s)

Omar Besseboua, Department of Agricultural Sciences, University M. Istambouli, Algeria
Abdelhanine Ayad, Department of Environment and Biological Sciences, University A. Mira; Laboratory of Research on Local Animal Products, Veterinary Institute, Ibn Khaldoun University, Algeria
Hama Benbarek, Department of Agricultural Sciences, University M. Istambouli; Laboratory of Research on Local Animal Products, Veterinary Institute, Ibn Khaldoun University, Algeria


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Abstract

This study was conducted to determine the effect of maternally derived antibody (MDA) on live vaccine against infectious bursal disease. A total of 140 chicks selected from vaccinated parent stock were used in this investigation. In a preset vaccination schedule, blood samples were collected to check for the actual effect. It was noticed that on day 1 the chicks contained a high level (6400.54 ± 2993.67) of maternally derived antibody that gradually decreased below a positive level within 21 days (365.86 ± 634.46). It was found that a high level of MDA interferes with the vaccine virus, resulting in no immune response. For better immune response, it is suggested that the chickens should be vaccinated at day 21, as the uniformity of MDA is poor (coefficient of the variation [CV] > 30%), and boosted at day 28. Indeed, two vaccinations are necessary to achieve good protection against infectious bursal disease virus of the entire flock.

Keywords

IBV virus, maternally derived antibody, vaccination, chickens.

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Crossref Citations

1. Vaccination Against Infectious Bursal Disease Virus (IBDV) in Broiler Birds in Mozambique: Are We Doing Enough?
E.F. Muchanga, E.R.C. Frechaut, P. Taunde, O. Nhambirre, A.M. Junior, C.G. Bila
International Journal of Poultry Science  vol: 14  issue: 12  first page: 644  year: 2015  
doi: 10.3923/ijps.2015.644.646